Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9113235 | 1.00 | LMNA (0.48) | LMNAHIF1AKDM4EMAPK1SLC6A4 | |
| Acetic Acid SCHEMBL9844917 | 0.86 | LMNA (0.48) | LMNASLC6A4 | |
| Oxalic Acid SCHEMBL28079978 | 0.86 | LMNA (0.48) | LMNAHIF1ASLC6A4ADRA2AADRA2C | |
| Benzene SCHEMBL28170835 | 0.84 | SLC6A4 (0.56) | LMNASLC6A4 | |
| SCHEMBL170928 | 0.84 | SLC6A4 (0.56) | LMNASLC6A4 | |
| SCHEMBL176808 | 0.84 | SLC6A4 (0.56) | LMNASLC6A4 | |
| SCHEMBL43945 | 0.84 | SLC6A4 (0.56) | LMNASLC6A4 | |
| SCHEMBL29503095 | 0.84 | SLC6A4 (0.56) | LMNASLC6A4 | |
| Iodide SCHEMBL6672339 | 0.82 | SLC6A4 (0.54) | LMNASLC6A4 | |
| Hydrochloric Acid SCHEMBL6852974 | 0.82 | SLC6A4 (0.54) | LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101277926-A | Method of obtaining 3,3-diphenylpropylamines | INTERQUIM SA (ES) | 2008-10-01 | — | — | CN | disclosed |