Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27884559 | 0.81 | KDM4E (0.31) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27667512 | 0.81 | KDM4E (0.31) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27770294 | 0.79 | KDM4E (0.30) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27794731 | 0.74 | AKT1 (0.36) | ALDH1A1 | |
| Propionic Acid SCHEMBL28908435 | 0.73 | FFAR3 (0.39) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| Ethoxycarbonyl Group SCHEMBL28602754 | 0.72 | — | — | |
| Ethoxycarbonyl Group SCHEMBL28765700 | 0.70 | RAB9A (0.40) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| Ethoxycarbonyl Group SCHEMBL27586257 | 0.69 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27865983 | 0.69 | LMNA (0.35) | NPC1ALDH1A1RAB9AKDM4E | |
| Ethoxycarbonyl Group SCHEMBL27405664 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985438-B | As the C-28 acid amides of the modified C-3 betulinic acid derivative of the ripe inhibitor of HIV | BRISTOL-MYERS SQUIBB CO. (US) | 2016-05-18 | — | — | CN | disclosed |
| CN-104903320-A | Nitrogen-containing heterocylic compound or salt thereof | FUJIFILM CORP | 2015-09-09 | — | — | CN | disclosed |
| CN-102388032-B | Substituted piperidines as CCR3 antagonists | BOEHRINGER INGELHEIM INT | 2015-01-14 | — | — | CN | disclosed |
| CN-104203237-A | Amidine-substituted beta-lactam compounds, their preparation and their use as antibacterial agents | AICURIS GMBH & CO KG | 2014-12-10 | — | — | CN | disclosed |
| CN-102712620-B | 4-phenoxy-nicotinamide or 4-phenoxy-pyrimidine-5-carboxamide compounds | HOFFMANN LA ROCHE | 2014-02-26 | — | — | CN | disclosed |
| CN-101263131-B | Urea glucokinase activators | TRANSTECH PHARMA INC | 2013-04-24 | — | — | CN | disclosed |
| CN-102985438-A | C-28 amides of modified C-3 betulinic acid derivatives as HIV maturation inhibitors | BRISTOL MYERS SQUIBB CO | 2013-03-20 | — | — | CN | disclosed |
| CN-101589039-B | Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme A delta-9 desaturase | MERCK FROSST CANADA LTD | 2012-09-05 | — | — | CN | disclosed |
| CN-102633748-A | Method for synthesizing 2-ethyl formate-5-bromine-1,3,4-thiadiazole | CGENE TECH SUZHOU CHINA CO LTD | 2012-08-15 | — | — | CN | disclosed |
| CN-102388032-A | Substituted piperidines as CCR3 antagonists | BOEHRINGER INGELHEIM INT | 2012-03-21 | — | — | CN | disclosed |
| CN-101528718-B | Modulators of glucocorticoid receptor and/or AP-1 and/or NF- κ B activity and uses thereof | BRISTOL MYERS SQUIBB CO | 2011-11-09 | — | — | CN | disclosed |
| CN-101589039-A | Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme A delta-9 desaturase | MERCK FROSST CANADA LTD (CA) | 2009-11-25 | — | — | CN | disclosed |
| CN-101528718-A | Modulators of glucocorticoid receptor and/or AP-1 and/or NF- κ B activity and uses thereof | BRISTOL MYERS SQUIBB CO (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101263131-A | Urea glucokinase activators | NOVO NORDISK AS (US) | 2008-09-10 | — | — | CN | disclosed |