Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27667512 | 0.81 | KDM4E (0.31) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27884559 | 0.81 | KDM4E (0.31) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27715619 | 0.79 | MEN1 (0.31) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27794731 | 0.74 | AKT1 (0.36) | — | |
| Ethoxycarbonyl Group SCHEMBL28116314 | 0.72 | — | — | |
| Ethoxycarbonyl Group SCHEMBL28765700 | 0.70 | RAB9A (0.40) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL23300856 | 0.70 | FAAH (0.31) | — | |
| 1,4-Dichlorobenzene SCHEMBL27842897 | 0.69 | HSD17B10 (0.42) | KDM4EPTGS2 | |
| Ethoxycarbonyl Group SCHEMBL5306888 | 0.67 | ALDH1A1 (0.38) | — | |
| Ethoxycarbonyl Group SCHEMBL1332384 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071526-A | The acid-addition salts of bridged piperazine derivatives | 阿森纽荣股份公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108884078-A | Glycosidase inhibitor | 阿森纽荣股份公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108884077-A | Glycosidase inhibitors | 阿森纽荣股份公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108884081-A | The method for separating the enantiomer of bridged piperazine derivatives | 阿森纽荣股份公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-103271906-A | Use of spiro-oxindole compounds as therapeutic agents | XENON PHARMACEUTICALS INC | 2013-09-04 | — | — | CN | disclosed |
| CN-101631546-A | Use of spiro-indolone compounds as therapeutic agents | XENON PHARMACEUTICALS INC | 2010-01-20 | — | — | CN | disclosed |