Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768685 | 0.76 | MAPK10 (0.42) | L3MBTL1LTA4HTSHRSMN1; SMN2RAB9A | |
| SCHEMBL27716343 | 0.72 | CYP2C19 (0.41) | L3MBTL1LTA4HSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10526948 | 0.70 | LTA4H (0.52) | L3MBTL1LTA4HTSHRSMN1; SMN2RAB9A | |
| Acetic Acid SCHEMBL11332370 | 0.69 | CYP2C19 (0.57) | L3MBTL1RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL27642524 | 0.68 | ADRA1D (0.33) | LTA4HTSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7341067 | 0.65 | LMNA (0.49) | L3MBTL1LTA4HSMN1; SMN2RAB9AMAPT | |
| SCHEMBL7341070 | 0.65 | LMNA (0.49) | L3MBTL1LTA4HSMN1; SMN2RAB9AMAPT | |
| SCHEMBL2590383 | 0.65 | NPC1 (0.56) | L3MBTL1SMN1; SMN2RAB9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL27933839 | 0.63 | NPC1 (0.55) | L3MBTL1SMN1; SMN2RAB9AMAPTNPC1 | |
| Acetic Acid Methyl Ester SCHEMBL31318381 | 0.63 | TAAR1 (0.67) | L3MBTL1TSHRSMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100372844-C | 2-imidazo-benzothiazoles as adenosine receptor ligands | HOFFMANN LA ROCHE (CH) | 2008-03-05 | — | — | CN | disclosed |