Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL27638989 | 0.89 | FFAR3 (0.56) | CYP19A1FFAR3CYP3A4LMNACYP1A2 | |
| Butyric Acid SCHEMBL4774927 | 0.86 | FFAR3 (0.50) | FFAR3CYP3A4LMNACYP1A2MAOA | |
| Bicarbonate SCHEMBL29147443 | 0.84 | MAPT (0.44) | CYP3A4LMNAMAPTKDM4EHIF1A | |
| Propionic Acid SCHEMBL10626620 | 0.80 | ACHE (0.59) | CYP19A1FFAR3CYP3A4LMNACYP1A2 | |
| Aniline SCHEMBL21145291 | 0.79 | TSHR (0.55) | CYP19A1FFAR3CYP3A4LMNACYP1A2 | |
| Propionic Acid SCHEMBL27717074 | 0.78 | FFAR3 (0.43) | FFAR3LMNACYP1A2MAPTCYP2C19 | |
| Propionic Acid SCHEMBL29093681 | 0.77 | ALDH1A1 (0.55) | CYP19A1LMNAMAPTKDM4EHIF1A | |
| Propionic Acid SCHEMBL11324817 | 0.75 | ALDH1A1 (0.64) | CYP19A1FFAR3CYP3A4LMNACYP1A2 | |
| Propionic Acid SCHEMBL27803358 | 0.75 | CA1 (0.50) | — | |
| Dalfampridine SCHEMBL7118612 | 0.74 | ALDH1A1 (0.56) | CYP19A1FFAR3CYP3A4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250103-A | Method for synthesizing ketoprofen by using ethylbenzene as raw material | WUXUE XUNDA PHARMACEUTICAL IND (CN) | 2008-08-27 | — | — | CN | claimed |
| CN-100540522-C | With ethylbenzene is the method for raw material synthesizing ketoprofen | WUXUE XUNDA PHARMACEUTICAL IND (CN) | 2009-09-16 | — | — | CN | disclosed |
| CN-101250103-A | Method for synthesizing ketoprofen by using ethylbenzene as raw material | WUXUE XUNDA PHARMACEUTICAL IND (CN) | 2008-08-27 | — | — | CN | disclosed |