Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708004 | 0.75 | SLC22A12 (0.45) | ALDH1A1MEN1KMT2ACNR2MAPT | |
| SCHEMBL27789553 | 0.74 | SAE1 (0.34) | MEN1KMT2APOLBCHRM1CNR2 | |
| SCHEMBL15712348 | 0.73 | ADORA1 (0.53) | ALDH1A1LMNAHTTNPSR1GAA | |
| SCHEMBL28045859 | 0.71 | POLB (0.41) | ALDH1A1LMNAHTTNPSR1KMT2A | |
| SCHEMBL1537114 | 0.70 | GRM2 (0.42) | ALDH1A1LMNATDP1SMN1; SMN2HTT | |
| SCHEMBL1083610 | 0.69 | GRM2 (0.41) | ALDH1A1LMNATDP1SMN1; SMN2HTT | |
| SCHEMBL27728387 | 0.69 | POLB (0.72) | ALDH1A1LMNASMN1; SMN2HTTNPSR1 | |
| SCHEMBL2069888 | 0.69 | LMNA (0.65) | LMNAL3MBTL1TP53CHRM1CNR2 | |
| SCHEMBL6086528 | 0.68 | ALDH1A1 (0.61) | ALDH1A1LMNATDP1SMN1; SMN2HTT | |
| SCHEMBL28774047 | 0.68 | PARP1 (0.52) | ALDH1A1LMNATDP1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101263136-A | Benzimidazole derivatives as 5-HT6, 5-HT24 | HOFFMANN LA ROCHE (CH) | 2008-09-10 | — | — | CN | disclosed |