SCHEMBL27716628

SCHEMBL27716628

O=C(O)c1ccc(Oc2ccccc2NC(=O)c2cccc(Cl)c2)cc1

nearest known ligand 0.77

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PYGM P11217 5/20 0.77
PYGL P06737 3/20 0.77
SMN1; SMN2 Q16637 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 2/20 0.58
SERPINE1 P05121 1/20 0.55
NPSR1 Q6W5P4 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
ALOX12 P18054 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
KCNK3 O14649 1/20 0.51
KCNK9 Q9NPC2 1/20 0.51
MAPK1 P28482 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27716773 0.90 PYGM (0.63) PYGMPYGLSMN1; SMN2L3MBTL1LMNA
SCHEMBL27716651 0.87 L3MBTL1 (0.64) PYGMPYGLSMN1; SMN2L3MBTL1LMNA
SCHEMBL6432816 0.87 PYGL (1.00) PYGMPYGL
SCHEMBL27716717 0.87 CACNA1H (0.60) PYGMPYGLSMN1; SMN2L3MBTL1LMNA
SCHEMBL27716603 0.86 PYGM (0.58) PYGMPYGLSMN1; SMN2L3MBTL1LMNA
SCHEMBL27716649 0.85 MAPT (0.58) PYGMPYGLSMN1; SMN2L3MBTL1LMNA
SCHEMBL27696853 0.84 PYGM (0.78) PYGMPYGLSMN1; SMN2MAPTNPSR1
SCHEMBL27696838 0.84 L3MBTL1 (0.57) PYGMPYGLSMN1; SMN2L3MBTL1LMNA
SCHEMBL27696835 0.82 PYGM (0.54) PYGMPYGLSMN1; SMN2L3MBTL1LMNA
SCHEMBL27716705 0.81 MAPT (0.87) PYGMPYGLSMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101094829-A Novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2007-12-26 CN disclosed