Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744353 | 0.63 | SIGMAR1 (0.55) | SIGMAR1ADRA2ATMEM97 | |
| SCHEMBL13892729 | 0.62 | HTR2A (0.32) | ADRA2A | |
| SCHEMBL4900253 | 0.62 | HSP90AA1 (0.37) | SIGMAR1ADRA2ATMEM97 | |
| SCHEMBL30861792 | 0.62 | HSP90AA1 (0.37) | SIGMAR1ADRA2ATMEM97 | |
| SCHEMBL8058883 | 0.61 | SIGMAR1 (0.36) | SIGMAR1ADRA2ATMEM97ALDH1A1MAPT | |
| SCHEMBL27873251 | 0.61 | HTR2A (0.33) | — | |
| SCHEMBL7719400 | 0.60 | NOTUM (0.36) | SIGMAR1ADRA2A | |
| SCHEMBL27519254 | 0.60 | HTR2A (0.33) | — | |
| SCHEMBL28316061 | 0.60 | — | — | |
| SCHEMBL29215252 | 0.59 | HTR2A (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282957-A | New pharmaceutical compounds | ORION CORP (FI) | 2008-10-08 | — | — | CN | disclosed |