Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30861792 | 1.00 | HSP90AA1 (0.37) | HSP90AA1PAX8MAOAMAOBADRA2A | |
| SCHEMBL10262549 | 0.86 | HSP90AA1 (0.33) | HSP90AA1PAX8MAOAMAOBADRA2A | |
| SCHEMBL29309181 | 0.82 | ALDH1A1 (0.41) | ADRA2ASIGMAR1HTR2CHTR2BTSHR | |
| SCHEMBL21701193 | 0.81 | GPR3 (0.36) | HSP90AA1PAX8TMEM97GPR3 | |
| SCHEMBL7400483 | 0.78 | LGALS8 (0.36) | HSP90AA1PAX8TSHR | |
| SCHEMBL7400440 | 0.74 | ATM (0.43) | HSP90AA1PAX8TSHR | |
| SCHEMBL8408677 | 0.74 | HSP90AA1 (0.30) | HSP90AA1PAX8 | |
| SCHEMBL5151902 | 0.73 | THRB (0.36) | MAOAMAOBADRA2AHTR2CHTR2A | |
| SCHEMBL10616744 | 0.72 | TOP2A (0.33) | ADRA2ASIGMAR1HTR2CHTR2AHTR2B | |
| SCHEMBL7021519 | 0.72 | MAPT (0.32) | MAOACA2HTR2CHTR2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040635-A1 | NANOPARTICLES CONTAINING MULTIPLE CLEAVABLE PRODUGS FOR CANCER THERAPY | THE UNIVERSITY OF CHICAGO (US) | 2022-02-24 | — | — | WO | disclosed |
| US-9968683-B2 | Method for conjugating molecules | ORGANOLINX CORP. (CA) | 2018-05-15 | — | — | US | disclosed |
| US-9968683-B2 | Method for conjugating molecules | ORGANOLINX CORP. (CA) | 2018-05-15 | — | — | US | disclosed |
| US-20160206748-A1 | METHOD FOR CONJUGATING MOLECULES | ORGANOLINX CORP. (CA) | 2016-07-21 | — | — | US | disclosed |
| EP-1738646-B1 | Forming germicidal aromatic dialdehydes with acetals | ETHICON INC (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20080110763-A1 | Method For Producing Alkoxylated 2,5-Dihydrofuran But-2-Ene Derivatives Or Tetra-1,1,4,4-Alkoxylated But-2-Ene Derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-15 | — | — | US | disclosed |
| US-7291649-B2 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291649-B2 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-20070004808-A1 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. | 2007-01-04 | — | — | US | disclosed |
| US-20070004808-A1 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. | 2007-01-04 | — | — | US | disclosed |
| EP-1738646-A2 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. (US) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004808-A1 | Forming germicidal aromatic dialdehydes with acetals | ALPG, DDT, ACR | HSP90AA1 382/4885PAX8 1590/4885MAOA 225/4885 |
| US-20080110763-A1 | Method For Producing Alkoxylated 2,5-Dihydrofuran But-2-Ene Derivatives Or Tetra-1,1,4,4-Alkoxylated But-2-Ene Derivatives | CYP2E1, ADH1C, ADH1A | HSP90AA1 3767/4885PAX8 4786/4885MAOA 1291/4885 |
| US-20160206748-A1 | METHOD FOR CONJUGATING MOLECULES | AADAC, DDT, ALDH3A1 | HSP90AA1 2125/4885PAX8 2239/4885MAOA 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.