Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738294 | 0.84 | NR4A1 (0.38) | HTTALDH1A1MAPTTDP1POLB | |
| SCHEMBL544435 | 0.82 | TDP1 (0.43) | HTTALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL3101957 | 0.81 | MAPT (0.46) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL11627382 | 0.79 | ALPL (0.47) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL11625776 | 0.77 | ALPL (0.43) | HTTALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL11623279 | 0.75 | SMN1; SMN2 (0.53) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL11623960 | 0.74 | APEX1 (0.57) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL11290098 | 0.74 | ALDH1A1 (0.51) | HTTALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL11627411 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1MAPTTDP1MEN1POLB | |
| SCHEMBL11627076 | 0.73 | MEN1 (0.46) | ALDH1A1MAPTTDP1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273019-A | Novel benzimidazole and benzothiazole derivatives, method for preparing same, use thereof as drugs, pharmaceutical compositions and novel use especially as C-Met inhibitors | AVENTIS PHARMA SA (FR) | 2008-09-24 | — | — | CN | disclosed |