Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717692 | 0.76 | APP (0.59) | RAB9ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL27411410 | 0.76 | APP (0.64) | RAB9ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL11364848 | 0.76 | MAPT (0.61) | RAB9ALMNAALDH1A1CYP2C19HPGD | |
| Hydrochloric Acid SCHEMBL17200380 | 0.76 | NFE2L2 (0.48) | RAB9ALMNAALDH1A1CYP2C19MAPT | |
| SCHEMBL7412157 | 0.76 | APP (0.59) | CYP2C19APP | |
| SCHEMBL6015209 | 0.76 | ALDH1A1 (0.52) | RAB9ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL11363584 | 0.76 | APP (0.59) | CYP2C19APP | |
| SCHEMBL11364849 | 0.76 | MAPT (0.61) | RAB9ALMNAALDH1A1CYP2C19HPGD | |
| SCHEMBL6015208 | 0.76 | ALDH1A1 (0.52) | RAB9ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL9679616 | 0.76 | ALDH1A1 (0.61) | RAB9AALDH1A1CYP2C19KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296906-A | (hetero)aryl compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INT (DE) | 2008-10-29 | — | — | CN | disclosed |