Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HBB | P68871 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015209 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRHDAC8MAPTSMN1; SMN2 | |
| Styrene SCHEMBL26089496 | 0.89 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8LMNATDP1 | |
| SCHEMBL4993147 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRAPPTDP1RELA | |
| Hydrochloric Acid SCHEMBL17200380 | 0.76 | NFE2L2 (0.48) | ALDH1A1TSHRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL11364848 | 0.76 | MAPT (0.61) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27717643 | 0.76 | RAB9A (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7412157 | 0.76 | APP (0.59) | APPTRPA1PTGS1 | |
| SCHEMBL11363584 | 0.76 | APP (0.59) | APPTRPA1PTGS1 | |
| SCHEMBL11364849 | 0.76 | MAPT (0.61) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27717692 | 0.76 | APP (0.59) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091274-B2 | A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1318172-B1 | Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black | GOODYEAR TIRE & RUBBER (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-0924227-B1 | Conjugated diolefin-based copolymer rubber and composition thereof | JSR CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-20030125448-A1 | A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-07-03 | — | — | US | disclosed |
| EP-1318172-A1 | Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6191234-B1 | CONJUGATED DIENE-AROMATIC VINYL COPOLYMER OBTAINED BY MODIFYING POLYMER WITH A AMINO GROUP IS USED TO IMPROVE WET SKID RESISTANCE, WEAR RESISTANCE OF AUTOMOBILE TIRE TREAD | JSR CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-1000970-A1 | Polymodal conjugated diolefin vinyl aromate rubber composition | JSR Corporation (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0924227-A1 | Conjugated diolefin-based copolymer rubber and composition thereof | JSR Corporation (JP) | 1999-06-23 | — | — | EP | disclosed |