Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717893 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2RECQLHTR7ACHECCR3 | |
| SCHEMBL27739137 | 0.99 | HTR7 (0.56) | SMN1; SMN2RECQLHTR7ACHECCR3 | |
| SCHEMBL4467334 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL3709310 | 0.82 | RECQL (0.70) | SMN1; SMN2RECQLACHECCR3KDM4E | |
| Hydrochloric Acid SCHEMBL10317429 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL4062103 | 0.82 | RECQL (0.60) | SMN1; SMN2RECQLACHECCR3TSHR | |
| SCHEMBL1206086 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3706762 | 0.81 | RECQL (0.68) | SMN1; SMN2RECQLACHECCR3KDM4E | |
| SCHEMBL7306412 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2RECQLHTR7ACHEKDM4E | |
| SCHEMBL1206024 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273021-A | Selected CGRP antagonists, methods for the production thereof and their use as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2008-09-24 | — | — | CN | disclosed |