Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305780 | 0.95 | SMN1; SMN2 (0.43) | SMN1; SMN2ABL1RIN1RECQLOPRL1 | |
| SCHEMBL7306453 | 0.91 | ALDH1A1 (0.42) | SMN1; SMN2ABL1RIN1RECQLCACNA1G | |
| SCHEMBL7305616 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2RECQLOPRL1OPRM1ALDH1A1 | |
| SCHEMBL7314659 | 0.88 | ALDH1A1 (0.43) | SMN1; SMN2RECQLALDH1A1KDM4EACHE | |
| SCHEMBL7304933 | 0.86 | ALDH1A1 (0.40) | SMN1; SMN2RECQLOPRL1OPRM1ALDH1A1 | |
| SCHEMBL7314570 | 0.86 | CACNA1G (0.43) | SMN1; SMN2CACNA1GALDH1A1HTR7 | |
| SCHEMBL7311883 | 0.86 | HTR7 (0.43) | CACNA1GALDH1A1HTR7 | |
| SCHEMBL7309384 | 0.86 | CHRM2 (0.43) | SMN1; SMN2CACNA1GALDH1A1HTR7 | |
| SCHEMBL7308778 | 0.86 | LTA4H (0.42) | ABL1RIN1CACNA1GACHELTA4H | |
| SCHEMBL7303493 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2OPRM1ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |