Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.64 |
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280786 | 0.95 | ACMSD (0.58) | ACMSDKMOTBK1KDM4ETDP1 | |
| SCHEMBL27545241 | 0.88 | ACMSD (0.53) | ACMSDKMOTBK1KDM4ETDP1 | |
| SCHEMBL3985016 | 0.87 | ACMSD (0.51) | ACMSDKMOTBK1KDM4ETDP1 | |
| SCHEMBL28283624 | 0.87 | ACMSD (0.69) | ACMSDKMOTBK1KDM4ETDP1 | |
| SCHEMBL23374556 | 0.84 | ACMSD (0.75) | ACMSDKMOTBK1KDM4ETDP1 | |
| SCHEMBL27636958 | 0.83 | ACMSD (0.47) | ACMSDKMOTBK1KDM4ETDP1 | |
| SCHEMBL26800328 | 0.81 | KDM4E (0.54) | ACMSDKDM4ETDP1HTTKMT2A | |
| SCHEMBL21857477 | 0.81 | ACMSD (0.44) | ACMSDTBK1KDM4ETDP1KMT2A | |
| SCHEMBL27592888 | 0.81 | ACMSD (0.76) | ACMSDKMOTBK1KDM4ETDP1 | |
| SCHEMBL3901048 | 0.80 | ACMSD (0.64) | ACMSDKMOTBK1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101072775-A | Novel mch receptor antagonists | LILLY CO ELI (US) | 2007-11-14 | — | — | CN | disclosed |