Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280786 | 0.88 | ACMSD (0.58) | ACMSDTBK1IKBKEALDH1A1KDM4E | |
| SCHEMBL27718282 | 0.83 | ACMSD (0.64) | ACMSDTBK1IKBKEALDH1A1KDM4E | |
| SCHEMBL27512856 | 0.77 | ACMSD (0.45) | ACMSDTBK1IKBKEALDH1A1KDM4E | |
| SCHEMBL28705515 | 0.74 | KDM1A (0.40) | CYP3A4 | |
| SCHEMBL29156207 | 0.73 | ACMSD (0.69) | ACMSDTBK1IKBKEKDM4EHSD17B10 | |
| SCHEMBL21857477 | 0.72 | ACMSD (0.44) | ACMSDTBK1IKBKEALDH1A1KDM4E | |
| SCHEMBL27545241 | 0.72 | ACMSD (0.53) | ACMSDTBK1ALDH1A1KDM4ETDP1 | |
| SCHEMBL28582512 | 0.72 | TRPM8 (0.34) | ACMSD | |
| SCHEMBL3985016 | 0.71 | ACMSD (0.51) | ACMSDTBK1ALDH1A1KDM4ETDP1 | |
| SCHEMBL28283624 | 0.71 | ACMSD (0.69) | ACMSDTBK1IKBKEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1893941-A | Fused-ring compounds and use thereof as drugs | JAPAN TOBACCO INC (JP) | 2007-01-10 | — | — | CN | disclosed |
| CN-1798740-A | Nitrogen-containing heteroaryl derivatives | GENELABS TECH INC (US) | 2006-07-05 | — | — | CN | disclosed |