Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.58 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.47 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718282 | 0.95 | ACMSD (0.64) | ACMSDTBK1IKBKEKMOALDH1A1 | |
| SCHEMBL27636958 | 0.88 | ACMSD (0.47) | ACMSDTBK1IKBKEKMOALDH1A1 | |
| SCHEMBL27512856 | 0.85 | ACMSD (0.45) | ACMSDTBK1IKBKEKMOALDH1A1 | |
| SCHEMBL29156207 | 0.84 | ACMSD (0.69) | ACMSDTBK1IKBKEKMOKDM4E | |
| SCHEMBL21857477 | 0.83 | ACMSD (0.44) | ACMSDTBK1IKBKEALDH1A1KDM4E | |
| SCHEMBL27545241 | 0.83 | ACMSD (0.53) | ACMSDTBK1KMOALDH1A1KDM4E | |
| SCHEMBL3985016 | 0.81 | ACMSD (0.51) | ACMSDTBK1KMOALDH1A1KDM4E | |
| SCHEMBL28283624 | 0.81 | ACMSD (0.69) | ACMSDTBK1IKBKEKMOALDH1A1 | |
| SCHEMBL31422825 | 0.81 | ACMSD (0.42) | ACMSDTBK1IKBKEKMOALDH1A1 | |
| SCHEMBL30280751 | 0.81 | ALDH1A1 (0.55) | ACMSDALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |