Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27443616 | 0.88 | ALOX5 (0.53) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL27739386 | 0.88 | SMN1; SMN2 (0.53) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL11373929 | 0.80 | RAB9A (0.55) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL10653229 | 0.78 | RAB9A (0.58) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL4786698 | 0.78 | HPGD (0.56) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL3963337 | 0.76 | HPGD (0.60) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL29152499 | 0.76 | HPGD (0.53) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL5536307 | 0.74 | HPGD (0.66) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL8669504 | 0.74 | HPGD (0.48) | HPGDCYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL7593598 | 0.73 | PKM (0.55) | HPGDCYP1A2CYP2C19CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100406013-C | Camptothecin derivatives | CALIFORNIA PACIFIC MED CENTER (US) | 2008-07-30 | — | — | CN | disclosed |