Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208445 | 0.84 | CYP4F2 (0.60) | ALDH1A1KDM4ESMN1; SMN2LMNACYP4F2 | |
| SCHEMBL27718338 | 0.82 | CYP1A2 (0.49) | ALDH1A1KDM4ESMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6174947 | 0.81 | PKM (0.54) | ALDH1A1KDM4ESMN1; SMN2LMNATOP2A | |
| SCHEMBL5717650 | 0.81 | CYP4F2 (0.63) | ALDH1A1KDM4ESMN1; SMN2LMNACYP4F2 | |
| SCHEMBL5538129 | 0.79 | KDM4E (0.53) | ALDH1A1KDM4ESMN1; SMN2LMNATOP2A | |
| SCHEMBL24762616 | 0.76 | LMNA (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNACYP1A2 | |
| SCHEMBL27783318 | 0.75 | LMNA (0.43) | ALDH1A1KDM4ESMN1; SMN2LMNACYP4F2 | |
| SCHEMBL27636037 | 0.75 | PKM (0.46) | ALDH1A1KDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL28661753 | 0.75 | CYP1A2 (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNACYP4F2 | |
| SCHEMBL29852763 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2LMNACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100406013-C | Camptothecin derivatives | CALIFORNIA PACIFIC MED CENTER (US) | 2008-07-30 | — | — | CN | disclosed |