Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.60 |
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717650 | 0.91 | CYP4F2 (0.63) | CYP4F2CYP4A11TOP2AMAPTLMNA | |
| SCHEMBL4059940 | 0.85 | KDM4E (0.50) | MAPTKDM4EALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL6174947 | 0.85 | PKM (0.54) | TOP2AMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL27718342 | 0.84 | ALDH1A1 (0.46) | CYP4F2CYP4A11TOP2ALMNAKDM4E | |
| SCHEMBL1362448 | 0.83 | KMT2A (0.53) | CYP4F2CYP4A11TOP2AMAPTLMNA | |
| SCHEMBL590805 | 0.82 | MTNR1A (0.65) | LMNAKDM4EALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL21820692 | 0.81 | LOXL2 (0.49) | ALDH1A1CYP1A2LOXL2 | |
| SCHEMBL2699530 | 0.80 | MTNR1A (0.54) | CYP4F2CYP4A11LMNAKDM4EALDH1A1 | |
| SCHEMBL1650885 | 0.79 | CYP1A2 (0.55) | LMNAKDM4EALDH1A1KMT2ACYP1A2 | |
| SCHEMBL69660 | 0.78 | CYP4F2 (0.86) | CYP4F2CYP4A11MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-0922050-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997042205-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | disclosed |