Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 4/20 | 0.49 |
| ▸ | GABRD | O14764 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449636 | 0.89 | GRIN1 (0.51) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL6044996 | 0.87 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL13988189 | 0.87 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL11060164 | 0.87 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL5481340 | 0.87 | MEN1 (0.52) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL6045004 | 0.87 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL11345742 | 0.87 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL497658 | 0.87 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL497657 | 0.87 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL5481343 | 0.87 | MEN1 (0.52) | MEN1KMT2AAKR1B10AKR1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100378118-C | Pharmaceutical composition with appetite suppressant activity | CSIR (ZA) | 2008-04-02 | — | — | CN | disclosed |