Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 4/20 | 0.48 |
| ▸ | GABRD | O14764 | 4/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481340 | 1.00 | MEN1 (0.52) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL27718581 | 0.87 | MEN1 (0.53) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL6045004 | 0.86 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL13988189 | 0.86 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL497657 | 0.86 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL6044996 | 0.86 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL11345742 | 0.86 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL497658 | 0.86 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL11060164 | 0.86 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL11696291 | 0.84 | MEN1 (0.57) | MEN1KMT2AAKR1B10AKR1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270584-A1 | Process for the Preparation of Steroidal Carbothioic Acid Derivatives and Intermediates | AXELLIA PHARMACEUTICALS APS (DK) | 2007-11-22 | — | — | US | claimed |
| EP-1611149-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | Alpharma APS (DK) | 2006-01-04 | — | — | EP | claimed |
| WO-2004087731-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | ALPHARMA APS (DK) | 2004-10-14 | — | — | WO | claimed |
| US-20070270584-A1 | Process for the Preparation of Steroidal Carbothioic Acid Derivatives and Intermediates | AXELLIA PHARMACEUTICALS APS (DK) | 2007-11-22 | — | — | US | disclosed |
| EP-1611149-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | Alpharma APS (DK) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087731-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | ALPHARMA APS (DK) | 2004-10-14 | — | — | WO | disclosed |
| US-4650610-A | Androstane carbothioic acids | GLAXO GROUP LIMITED (GB) | 1987-03-17 | — | — | US | disclosed |
| US-4578221-A | Androstane carbothioic acids | GLAXO GROUP LIMITED (GB) | 1986-03-25 | — | — | US | disclosed |
| US-4335121-A | TOPICAL ANTIINFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 1982-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270584-A1 | Process for the Preparation of Steroidal Carbothioic Acid Derivatives and Intermediates | CYP17A1, HSD17B7, NR5A1 | MEN1 3718/4885KMT2A 2780/4885AKR1B10 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.