SCHEMBL2771865

SCHEMBL2771865

COC(=O)c1cc(C(=O)OC)cc(S(=O)(=O)[O-])c1.OCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.40
CYP4A11 Q02928 3/20 0.39
CYP4F2 P78329 2/20 0.39
TSHR P16473 1/20 0.38
HPGD P15428 2/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
PKM P14618 1/20 0.37
CA2 P00918 2/20 0.37
LMNA P02545 1/20 0.36
POLB P06746 2/20 0.36
FOLH1 Q04609 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2769023 0.93 TSHR (0.43) PTGS2CYP4A11CYP4F2TSHRHPGD
Butyltriphenylphosphonium SCHEMBL6729607 0.91 L3MBTL1 (0.43) PTGS2TSHRCA2LMNAL3MBTL1
SCHEMBL11679019 0.89 L3MBTL1 (0.42) L3MBTL1
SCHEMBL6735230 0.85 LMNA (0.44) PTGS2TSHRHPGDKDM4EALDH1A1
SCHEMBL6729402 0.83 HPGD (0.43) PTGS2TSHRHPGDKDM4EALDH1A1
Tetraphenylphosphonium SCHEMBL6735186 0.82 TSHR (0.46) PTGS2TSHRHPGDKDM4EALDH1A1
SCHEMBL10484509 0.81 POLB (0.46) PTGS2TSHRHPGDKDM4EALDH1A1
SCHEMBL5078946 0.81 L3MBTL1 (0.43) PTGS2TSHRHPGDKDM4EALDH1A1
SCHEMBL3137310 0.81 TSHR (0.45) PTGS2TSHRHPGDKDM4EALDH1A1
SCHEMBL10484536 0.80 SLC7A5 (0.49) CYP4A11CYP4F2HPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1929375-B1 BIASABLE TRANSFER MEMBER EASTMAN KODAK CO (US) 2010-04-28 EP disclosed
US-7540981-B2 Biasable transfer composition and member EASTMAN KODAK COMPANY (US) 2009-06-02 US disclosed
EP-1929375-A1 BIASABLE TRANSFER COMPOSITION AND MEMBER EASTMAN KODAK COMPANY (US) 2008-06-11 EP disclosed
WO-2007041054-A1 BIASABLE TRANSFER COMPOSITION AND MEMBER EASTMAN KODAK COMPANY (US) 2007-04-12 WO disclosed
US-20070075298-A1 Biasable transfer composition and member EASTMAN KODAK COMPANY 2007-04-05 US disclosed