Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27740043 | 0.81 | ALDH1A1 (0.43) | ABCC1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL19858749 | 0.74 | ABCC1 (0.51) | ABCC1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28494893 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL616634 | 0.73 | KCNA3 (0.53) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL1498759 | 0.71 | MEN1 (0.45) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL28709537 | 0.71 | LMNA (0.51) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11484964 | 0.71 | KCNA3 (0.51) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL218047 | 0.71 | KCNA3 (0.50) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7586296 | 0.70 | MAPT (0.54) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL5317324 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101291924-A | Isoindole-imide compounds and compositions comprising and methods of using the same | CELGENE CORP (US) | 2008-10-22 | — | — | CN | disclosed |