Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699323 | 0.83 | ALDH1A1 (0.32) | SMN1; SMN2KDM4EMAPTPKMTDP1 | |
| SCHEMBL596873 | 0.82 | MCL1 (0.36) | SMN1; SMN2TSHRKDM4EMAPTPKM | |
| SCHEMBL1632856 | 0.79 | MAPT (0.35) | SMN1; SMN2TSHRKDM4EMAPTPKM | |
| SCHEMBL1633719 | 0.78 | ALDH1A1 (0.41) | TSHRKDM4EMAPTPKMALDH1A1 | |
| SCHEMBL28573075 | 0.78 | LMNA (0.41) | SMN1; SMN2TSHRMAPTALDH1A1HPGD | |
| SCHEMBL22816343 | 0.77 | ALDH1A1 (0.35) | SMN1; SMN2TSHRKDM4EMAPTPKM | |
| SCHEMBL4299182 | 0.74 | MEN1 (0.47) | SMN1; SMN2MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL19778352 | 0.73 | ALDH1A1 (0.34) | SMN1; SMN2TSHRKDM4EMAPTPKM | |
| SCHEMBL10941412 | 0.72 | ALDH1A1 (0.35) | SMN1; SMN2KDM4EMAPTPKMTDP1 | |
| SCHEMBL1017813 | 0.71 | ABL1 (0.38) | TSHRKDM4EMAPTTDP1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163678-B | Pyridylmethylsulfone derivative | DAIICHI SANKYO CO LTD | 2012-01-04 | — | — | CN | disclosed |
| CN-101163678-A | Pyridylmethylsulfone derivative | DAIICHI SANKYO CO LTD (JP) | 2008-04-16 | — | — | CN | disclosed |