Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14882664 | 0.92 | CTSV (0.52) | CTSVCTSLLMNAHPGDMRGPRX4 | |
| SCHEMBL24140919 | 0.86 | MRGPRX4 (0.51) | CTSVCTSLLMNAHPGDMRGPRX4 | |
| SCHEMBL9617336 | 0.86 | MAPT (0.52) | CTSVCTSLLMNAHPGDMRGPRX4 | |
| SCHEMBL25365036 | 0.86 | CTSV (0.52) | CTSVCTSLLMNAHPGDMRGPRX4 | |
| SCHEMBL30892453 | 0.85 | CTSV (0.50) | CTSVCTSLLMNAHPGDMRGPRX4 | |
| SCHEMBL24983855 | 0.85 | CTSV (0.50) | CTSVCTSLLMNAHPGDMRGPRX4 | |
| SCHEMBL25877912 | 0.83 | PTGER1 (0.48) | CTSVCTSLLMNAHPGDMRGPRX4 | |
| SCHEMBL24983696 | 0.82 | LMNA (0.54) | CTSVCTSLLMNAHPGDBRD4 | |
| SCHEMBL6761323 | 0.82 | FOLH1 (0.52) | CTSVCTSLMRGPRX4FOLH1MEN1 | |
| SCHEMBL30141095 | 0.82 | FOLH1 (0.52) | CTSVCTSLMRGPRX4FOLH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309912-B | Oxazole compound and pharmaceutical composition | OTSUKA PHARMA CO LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-101309912-A | Oxazole compound and pharmaceutical composition | OTSUKA PHARMA CO LTD (JP) | 2008-11-19 | — | — | CN | disclosed |