Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741031 | 1.00 | MAPT (0.39) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL17844741 | 0.86 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL17844812 | 0.80 | MAPT (0.37) | MAPTMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL11127289 | 0.80 | CYP2C19 (0.37) | MAPTKMT2AALDH1A1CYP2C19CYP2D6 | |
| SCHEMBL5855848 | 0.79 | HCAR2 (0.44) | MAPTLMNAALDH1A1CYP2C19CYP2D6 | |
| SCHEMBL20482479 | 0.78 | KMT2A (0.48) | MAPTLMNAMEN1KMT2ATACR3 | |
| SCHEMBL28862367 | 0.78 | MAPT (0.47) | MAPTLMNAMEN1KMT2ATACR3 | |
| SCHEMBL29112408 | 0.77 | MAPT (0.46) | MAPTLMNAMEN1KMT2ATACR3 | |
| SCHEMBL27726323 | 0.77 | MAPT (0.46) | MAPTLMNAMEN1KMT2ATACR3 | |
| SCHEMBL27726319 | 0.77 | MAPT (0.46) | MAPTLMNAMEN1KMT2ATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300239-A | 7- (2-amino-1-hydroxy-ethyl) -4-hydroxybenzothiazol-2 (3H) -one derivatives as beta 2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | CN | disclosed |