Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.52 |
| ▸ | CA1 | P00915 | 12/20 | 0.52 |
| ▸ | CA9 | Q16790 | 10/20 | 0.52 |
| ▸ | CA12 | O43570 | 9/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL28279686 | 0.81 | CA2 (0.56) | CA2CA1CA9CA12CA14 | |
| Sulfanilamide SCHEMBL28066119 | 0.79 | CA2 (0.65) | CA2CA1CA9CA12CA14 | |
| Homocysteine SCHEMBL27563537 | 0.78 | PTGS1 (0.52) | GRM8GRM7GRM4SLC1A3SLC1A2 | |
| L-Homocysteine SCHEMBL31443069 | 0.76 | — | — | |
| L-Homocysteine SCHEMBL31443068 | 0.76 | PTGS1 (0.59) | GRM8GRM7GRM4SLC1A3SLC1A2 | |
| Sulfanilamide SCHEMBL8367210 | 0.75 | CA2 (0.65) | CA2CA1CA9CA12CA14 | |
| Homocysteine SCHEMBL7783696 | 0.74 | PTGS1 (0.52) | GRM8GRM7GRM4SLC1A3SLC1A2 | |
| Homocysteine SCHEMBL7785059 | 0.74 | PTGS1 (0.52) | GRM8GRM7GRM4SLC1A3SLC1A2 | |
| Sulfanilamide SCHEMBL20567505 | 0.74 | CA2 (0.77) | CA2CA1CA9CA12CA14 | |
| L-Homocysteine SCHEMBL7785056 | 0.74 | PTGS1 (0.52) | GRM8GRM7GRM4SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296937-B | Asymmetric synthesis of peptides | UNIV READING | 2012-05-09 | — | — | CN | disclosed |
| CN-101296937-A | Asymmetric synthesis of peptides | UNIV READING (GB) | 2008-10-29 | — | — | CN | disclosed |