Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.56 |
| ▸ | CA1 | P00915 | 12/20 | 0.56 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA12 | O43570 | 7/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Toluenesulfonamide SCHEMBL6645679 | 0.89 | CA2 (0.56) | CA2CA1CA9CA12CA7 | |
| P-Toluenesulfonamide SCHEMBL6645676 | 0.89 | CA2 (0.56) | CA2CA1CA9CA12CA7 | |
| P-Toluenesulfonamide SCHEMBL6642631 | 0.88 | CA2 (0.55) | CA2CA1CA9CA12CA7 | |
| P-Toluenesulfonamide SCHEMBL6642628 | 0.88 | CA2 (0.55) | CA2CA1CA9CA12CA7 | |
| Benzenesulfonamide SCHEMBL6894807 | 0.87 | CA2 (0.54) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL6894805 | 0.87 | CA2 (0.54) | CA2CA1CA9CA12CA14 | |
| Sulfanilamide SCHEMBL27720397 | 0.81 | CA2 (0.52) | CA2CA1CA9CA12CA14 | |
| 4-Nitroaniline SCHEMBL10381907 | 0.80 | GRM8 (0.49) | — | |
| 4-Nitroaniline SCHEMBL6705231 | 0.80 | GRM8 (0.49) | — | |
| Racemethionine SCHEMBL8704679 | 0.78 | PMP22 (0.53) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563496-B | Cell lines for recombinant protein and/or viral vector production | 星火治疗有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-109563496-A | The cell line produced for recombinant protein and/or viral vectors | 星火治疗有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-109563496-B | Cell lines for recombinant protein and/or viral vector production | 星火治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-109563496-A | The cell line produced for recombinant protein and/or viral vectors | 星火治疗有限公司 | 2019-04-02 | — | — | CN | disclosed |