Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.53 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035024 | 1.00 | GABBR2 (0.53) | GABBR2GABBR1CYP2C19CYP2D6SRC | |
| SCHEMBL8875068 | 0.83 | MTNR1A (0.47) | GABBR2GABBR1CYP2C19CYP2D6SRC | |
| SCHEMBL7666339 | 0.78 | CYP2C19 (0.48) | GABBR2GABBR1CYP2C19CYP2D6SRC | |
| 3,3-Diphenylpropanoic Acid SCHEMBL5283373 | 0.78 | GABBR2 (0.59) | GABBR2GABBR1CYP2C19CYP2D6SRC | |
| 3,3-Diphenylpropanoic Acid SCHEMBL66473 | 0.78 | GABBR2 (0.59) | GABBR2GABBR1CYP2C19CYP2D6SRC | |
| SCHEMBL10917931 | 0.77 | HPGD (0.44) | CYP2C19SRCLMNA | |
| SCHEMBL14071758 | 0.77 | FFAR1 (0.52) | GABBR2GABBR1CYP2C19CYP2D6SRC | |
| SCHEMBL3270768 | 0.77 | FFAR1 (0.52) | GABBR2GABBR1CYP2C19CYP2D6SRC | |
| 3,3-Diphenylpropanoic Acid SCHEMBL9100138 | 0.76 | GABBR2 (0.57) | GABBR2GABBR1CYP2C19CYP2D6SRC | |
| SCHEMBL12473262 | 0.76 | GABBR2 (0.57) | GABBR2GABBR1CYP2C19CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101171241-A | Chromen-4-one inhibitors of anti-apoptotic BCL-2 family members and the uses thereof | UNIV MICHIGAN (US) | 2008-04-30 | — | — | CN | disclosed |