SCHEMBL27720581

SCHEMBL27720581

CCn1cc(C(=O)Cl)nc1Cl

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
ABCC4 O15439 1/20 0.31
PKM P14618 1/20 0.31
PTGS1 P23219 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
NFKB1 P19838 1/20 0.30
BLM P54132 1/20 0.30
HSD17B10 Q99714 1/20 0.30
GABRA2 P47869 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28314805 0.71 L3MBTL1 (0.40) PTGS1GABRA2GABRB2
SCHEMBL25210856 0.70
SCHEMBL25211607 0.68
SCHEMBL28140203 0.65 ALDH1A1 (0.33) ALDH1A1LMNAMEN1ABCC4PKM
SCHEMBL999335 0.63 PTGS1 (0.37) ALDH1A1LMNAMEN1ABCC4PKM
SCHEMBL19069401 0.61 MEN1 (0.35) ALDH1A1LMNAMEN1ABCC4PKM
SCHEMBL6494245 0.61 RXFP1 (0.36) ALDH1A1LMNAMEN1ABCC4PKM
SCHEMBL9957515 0.60 LPO (0.32)
SCHEMBL23534481 0.60 RXFP1 (0.39) ALDH1A1
SCHEMBL22143206 0.60 NR4A2 (0.41) ALDH1A1MEN1KMT2AKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101307022-B Green synthetic method for methyl-3-ethyl-4-chlorin-5-pyrazol formyl chloride UNIV ZHEJIANG TECHNOLOGY 2010-12-22 CN claimed
CN-101307022-A Green synthetic method for methyl-3-ethyl-4-chlorin-5-pyrazol formyl chloride UNIV ZHEJIANG TECHNOLOGY (CN) 2008-11-19 CN claimed