Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28483245 | 0.87 | ESR1 (0.50) | LMNATDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3821882 | 0.79 | TDP1 (0.79) | LMNATDP1NPC1RAB9ARECQL | |
| SCHEMBL2539792 | 0.78 | TSHR (0.50) | LMNATDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL16673090 | 0.77 | TDP1 (0.76) | LMNATDP1NPC1RAB9ARECQL | |
| SCHEMBL6232820 | 0.77 | TDP1 (0.76) | LMNATDP1NPC1RAB9ARECQL | |
| SCHEMBL8896400 | 0.76 | LMNA (0.61) | LMNATDP1NPC1RAB9ARECQL | |
| SCHEMBL28444213 | 0.76 | LMNA (0.56) | LMNATDP1NPC1RAB9ARECQL | |
| SCHEMBL982156 | 0.76 | LMNA (0.65) | LMNATDP1NPC1RAB9ARECQL | |
| SCHEMBL1553490 | 0.76 | LMNA (0.65) | LMNATDP1NPC1RAB9ARECQL | |
| SCHEMBL27899569 | 0.76 | TSHR (0.48) | LMNATDP1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128424-A | Indole compound and use thereof | ONO PHARMACEUTICAL CO (JP) | 2008-02-20 | — | — | CN | disclosed |