Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | MST1R | Q04912 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28772251 | 0.86 | LTK (0.42) | LTKCDK5MST1RDYRK1ACLK4 | |
| SCHEMBL3048189 | 0.68 | CDK5 (0.62) | LTKCDK5MST1RDYRK1ACLK4 | |
| SCHEMBL27720812 | 0.60 | CFTR (0.36) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL27700209 | 0.59 | HSD17B10 (0.34) | HSD17B10 | |
| SCHEMBL6228215 | 0.58 | LTA4H (0.47) | LTKCDK5MST1RDYRK1ACLK4 | |
| SCHEMBL27790049 | 0.58 | MAPT (0.47) | LTKCDK5MST1RDYRK1ACLK4 | |
| SCHEMBL1308794 | 0.57 | GPR35 (0.46) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL18133656 | 0.57 | ERN1 (0.50) | LTKCDK5MST1RDYRK1ACLK4 | |
| SCHEMBL29945128 | 0.55 | LTA4H (0.47) | LTKCDK5MST1RDYRK1ACLK4 | |
| SCHEMBL9927346 | 0.55 | LTA4H (0.47) | LTKCDK5MST1RDYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163675-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO KK (JP) | 2008-04-16 | — | — | CN | disclosed |