Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498879 | 0.89 | CA12 (0.39) | PTPN1TP53 | |
| SCHEMBL27761505 | 0.89 | PPARA (0.47) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL497820 | 0.82 | RXRA (0.41) | PPARAMCL1RARB | |
| SCHEMBL27740953 | 0.81 | EGFR (0.37) | PPARAPTPN1RARB | |
| SCHEMBL8243911 | 0.79 | ESR1 (0.50) | PPARAPPARGPTPN11S1PR3TP53 | |
| SCHEMBL4369286 | 0.75 | PTPN11 (0.56) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL27761412 | 0.75 | PPARA (0.58) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL498276 | 0.74 | CA1 (0.47) | TP53 | |
| SCHEMBL25421342 | 0.74 | PPARA (0.65) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL498164 | 0.72 | THRA (0.36) | PPARAPPARGPTPN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029547-B1 | FXR AGONISTS | LILLY CO ELI (US) | 2010-04-28 | — | — | EP | disclosed |