Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735476 | 0.89 | ALDH1A1 (0.39) | MAPTALPLALDH1A1GAACYP3A4 | |
| SCHEMBL27844127 | 0.88 | MAPT (0.39) | MAPTNPC1RAB9AALPLALDH1A1 | |
| SCHEMBL27701156 | 0.79 | MAPT (0.31) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL27756114 | 0.78 | CYP1A2 (0.36) | MAPTNPC1ALDH1A1GAACYP3A4 | |
| SCHEMBL27527386 | 0.77 | AKR1B1 (0.39) | MAPTNPC1RAB9AALPLALDH1A1 | |
| SCHEMBL28101785 | 0.76 | AKR1B1 (0.41) | MAPTNPC1RAB9AALDH1A1GAA | |
| SCHEMBL27659878 | 0.75 | PARP1 (0.37) | MAPTHSD17B10MEN1KMT2APOLB | |
| SCHEMBL27756120 | 0.75 | CAPN9 (0.40) | MAPTNPC1RAB9AALDH1A1GAA | |
| SCHEMBL27804773 | 0.74 | ALDH1A1 (0.41) | MAPTPTPN1ALDH1A1GAACYP3A4 | |
| SCHEMBL9845500 | 0.74 | ALDH1A1 (0.44) | MAPTALPLALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101171015-A | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS INC (US) | 2008-04-30 | — | — | CN | disclosed |