Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721773 | 0.88 | RET (0.31) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL27721875 | 0.79 | MAPT (0.37) | MAPTMEN1GAAKMT2ATDP1 | |
| SCHEMBL27659878 | 0.78 | PARP1 (0.37) | MAPTMEN1KMT2A | |
| SCHEMBL28151077 | 0.77 | ALK (0.31) | MAPTKDM4EGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28394859 | 0.74 | CA9 (0.39) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL27873179 | 0.72 | — | — | |
| SCHEMBL27774969 | 0.70 | CNR2 (0.31) | — | |
| SCHEMBL27735476 | 0.70 | ALDH1A1 (0.39) | MAPTMEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL27590240 | 0.70 | KDM4E (0.33) | KDM4EMEN1GAAKMT2ACA9 | |
| SCHEMBL11558077 | 0.69 | ATAD2 (0.38) | KDM4ESMN1; SMN2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101171015-A | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS INC (US) | 2008-04-30 | — | — | CN | disclosed |