SCHEMBL27722305

SCHEMBL27722305

C(OCC1CO1)C1CO1.Cc1cccc(O)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.57
ALDH1A1 P00352 8/20 0.47
GLA P06280 1/20 0.47
TSHR P16473 5/20 0.42
TP53 P04637 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CYP3A4 P08684 2/20 0.42
HIF1A Q16665 2/20 0.42
TDP1 Q9NUW8 3/20 0.40
ATM Q13315 1/20 0.38
MAPK1 P28482 2/20 0.38
HPGD P15428 4/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALOX12 P18054 1/20 0.36
ADAMTS4 O75173 1/20 0.35
EGFR P00533 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3671558 0.91 ALDH1A1 (0.52) TRPA1ALDH1A1GLATSHRTP53
SCHEMBL28045493 0.91 ALDH1A1 (0.52) TRPA1ALDH1A1GLATSHRTP53
Pyrogallol SCHEMBL27626139 0.90 ALDH1A1 (0.44) TRPA1ALDH1A1GLATSHRTP53
SCHEMBL27859316 0.87 TRPA1 (0.57) TRPA1ALDH1A1GLATSHRTP53
Orthocresol SCHEMBL1287877 0.86 ALDH1A1 (0.54) TRPA1ALDH1A1GLATSHRTP53
SCHEMBL27944101 0.86 ALDH1A1 (0.46) TRPA1ALDH1A1GLATSHRTP53
Benzene SCHEMBL27574432 0.85 TRPA1 (0.55) TRPA1ALDH1A1GLATSHRTP53
Ammonia Solution, Strong SCHEMBL28677700 0.85 TRPA1 (0.55) TRPA1ALDH1A1GLATSHRTP53
SCHEMBL4847009 0.85 ALDH1A1 (0.41) TRPA1ALDH1A1GLATSHRTP53
Ethane SCHEMBL28184482 0.82 TSHR (0.42) ALDH1A1GLATSHRTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104039862-A Sulfide-extended epoxy resin and application of barrier coating thereof SUN CHEMICAL CORP 2014-09-10 CN claimed
CN-104039862-A Sulfide-extended epoxy resin and application of barrier coating thereof SUN CHEMICAL CORP 2014-09-10 CN disclosed
CN-102498146-A Polymer compositions and methods of making and using the same POLYMERIGHT INC 2012-06-13 CN disclosed
CN-101309992-A Mercaptan-hardened epoxy polymer compositions and processes for making and using same CHEVRON PHILLIPS CHEMICAL CO (US) 2008-11-19 CN disclosed