Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626781 | 0.80 | ACP3 (0.41) | ACP3HSD11B1CNR2CTSSMC4R | |
| SCHEMBL27742156 | 0.78 | ACP3 (0.37) | ACP3HSD11B1CNR2CTSSMC4R | |
| SCHEMBL5609116 | 0.78 | ACP3 (0.41) | ACP3HSD11B1CNR2MC4RCYP1A2 | |
| SCHEMBL27925756 | 0.78 | TAS1R3 (0.39) | CNR2MC4RCYP3A4CYP2C9MAPT | |
| SCHEMBL19879071 | 0.78 | MC4R (0.41) | ACP3HSD11B1CNR2MC4RCYP1A2 | |
| SCHEMBL27907690 | 0.77 | KCNK3 (0.37) | TSHRSLC6A4EPHX2PPARG | |
| SCHEMBL16442475 | 0.76 | P2RX7 (0.42) | ACP3HSD11B1CNR2MC4RCYP1A2 | |
| SCHEMBL21311456 | 0.76 | P2RX7 (0.42) | ACP3HSD11B1CNR2MC4RCYP1A2 | |
| SCHEMBL12944872 | 0.76 | MC4R (0.40) | ACP3HSD11B1CNR2MC4RCYP1A2 | |
| SCHEMBL1824153 | 0.76 | ESR1 (0.39) | ACP3MC4RCYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326155-B | Propionamide compounds as antiinflammatory agents | HOFFMANN LA ROCHE | 2012-06-20 | — | — | CN | disclosed |
| CN-101326169-B | Glucocorticoid receptor modulators as antiinflammatory agents | HOFFMANN LA ROCHE | 2011-11-16 | — | — | CN | disclosed |
| CN-101326155-A | Propionamide compounds as antiinflammatory agents | HOFFMANN LA ROCHE (CH) | 2008-12-17 | — | — | CN | disclosed |
| CN-101326169-A | Glucocorticoid receptor modulators as antiinflammatory agents | HOFFMANN LA ROCHE (CH) | 2008-12-17 | — | — | CN | disclosed |