Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643692 | 0.82 | CYP2D6 (0.36) | KCNK3KCNK9HDAC3HDAC1HDAC2 | |
| SCHEMBL6735343 | 0.81 | KCNK3 (0.37) | KCNK3KCNK9F2RHDAC3HDAC1 | |
| SCHEMBL19633875 | 0.80 | KCNK3 (0.38) | KCNK3KCNK9F2RPDE2AUBE2M | |
| SCHEMBL6195357 | 0.79 | KCNK3 (0.34) | KCNK3KCNK9HDAC3HDAC1HDAC2 | |
| SCHEMBL19633904 | 0.78 | KCNK3 (0.40) | KCNK3KCNK9F2RPDE2AUBE2M | |
| SCHEMBL27722652 | 0.77 | ACP3 (0.39) | SLC6A4PPARGTSHREPHX2 | |
| SCHEMBL27624241 | 0.76 | KCNK3 (0.44) | KCNK3KCNK9GAARXRARXRB | |
| SCHEMBL19505951 | 0.75 | DHFR (0.37) | KCNK3KCNK9F2RSLC6A2SLC6A4 | |
| SCHEMBL27925756 | 0.74 | TAS1R3 (0.39) | GAAALDH1A1 | |
| SCHEMBL16672591 | 0.73 | PPARG (0.43) | KCNK3KCNK9F2RPDE2AUBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103140476-A | Novel trpv3 modulators | ABBOTT LAB | 2013-06-05 | — | — | CN | disclosed |