Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Alanine SCHEMBL9092097 | 0.98 | ATM (0.40) | CYP1A2SMN1; SMN2MAPK1DPP7L3MBTL1 | |
| Succinic Acid SCHEMBL5411814 | 0.90 | SMN1; SMN2 (0.47) | CYP1A2SMN1; SMN2MAPK1DPP7L3MBTL1 | |
| Succinic Acid SCHEMBL5403541 | 0.87 | ATM (0.44) | CYP1A2SMN1; SMN2MAPK1DPP7L3MBTL1 | |
| Glutarate SCHEMBL5406232 | 0.86 | CYP1A2 (0.53) | CYP1A2SMN1; SMN2MAPK1L3MBTL1HTT | |
| Glycine SCHEMBL8830859 | 0.85 | GLRA1 (0.46) | CYP1A2SMN1; SMN2MAPK1DPP7L3MBTL1 | |
| Glycine SCHEMBL8830879 | 0.83 | GLRA1 (0.48) | CYP1A2SMN1; SMN2MAPK1DPP7L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8356810 | 0.82 | LMNA (0.59) | CYP1A2SMN1; SMN2MAPK1L3MBTL1ATM | |
| SCHEMBL4055560 | 0.81 | CYP1A2 (0.48) | CYP1A2SMN1; SMN2MAPK1L3MBTL1HTT | |
| SCHEMBL23963672 | 0.80 | ALDH1A1 (0.55) | DPP7L3MBTL1HTTATMALDH1A1 | |
| SCHEMBL1363949 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130709-B | 3-aminopropionic acid piperidine amide compound with HIV activity, synthetic method and application | 常州亚邦制药有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-103130709-B | 3-aminopropionic acid piperidine amide compound with HIV activity, synthetic method and application | 常州亚邦制药有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-102319184-B | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO CO LTD | 2015-03-25 | — | — | CN | disclosed |
| CN-103130709-A | 3-aminopropionic acid piperidine amide compound with HIV activity, synthetic method and application | CHANGZHOU YABANG PHARMACEUTICAL CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-103130709-A | 3-aminopropionic acid piperidine amide compound with HIV activity, synthetic method and application | CHANGZHOU YABANG PHARMACEUTICAL CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-102319184-A | Parakeratosis inhibitor, pore contracting agent and composition for external application | SHISEIDO CO LTD | 2012-01-18 | — | — | CN | disclosed |
| CN-101175470-B | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO CO LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-101267803-B | Wrinkle-improving agent | SHISEIDO CO LTD | 2011-06-08 | — | — | CN | disclosed |
| CN-101267803-A | Wrinkle-improving agent | SHISEIDO CO LTD (JP) | 2008-09-17 | — | — | CN | disclosed |
| CN-101175470-A | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |