Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | SORD | Q00796 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723001 | 0.80 | SLC6A7 (0.53) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL27722983 | 0.78 | GBA1 (0.59) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL30670461 | 0.77 | HCRTR1 (0.52) | — | |
| SCHEMBL30465895 | 0.77 | HCRTR1 (0.52) | — | |
| SCHEMBL28473270 | 0.77 | RET (0.56) | — | |
| SCHEMBL19893876 | 0.77 | KMT2A (0.36) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL8171578 | 0.76 | HRH4 (0.65) | KMT2AMEN1KDM4EHSD17B10HPGD | |
| SCHEMBL1708189 | 0.76 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL13033934 | 0.76 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL10410296 | 0.75 | CRHBP (0.64) | MAPTTSHRHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193635-A | Multicyclic compounds and methods of their use | LEXICON GENETICS INC (US) | 2008-06-04 | — | — | CN | claimed |
| CN-101193635-A | Multicyclic compounds and methods of their use | LEXICON GENETICS INC (US) | 2008-06-04 | — | — | CN | disclosed |