Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723333 | 0.89 | — | — | |
| SCHEMBL27723267 | 0.89 | SLC22A12 (0.36) | CYP3A4CYP2C19GAACYP3A5 | |
| SCHEMBL27723227 | 0.87 | GLO1 (0.36) | CYP3A4CYP2C19ALDH1A1CYP19A1SMN1; SMN2 | |
| SCHEMBL28944101 | 0.87 | KCNA5 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27864967 | 0.86 | KCNA5 (0.33) | — | |
| SCHEMBL27723217 | 0.84 | NFE2L2 (0.35) | NFE2L2 | |
| SCHEMBL27744209 | 0.83 | CYP3A4 (0.34) | CYP3A4CYP2C19GAAGNRHR | |
| SCHEMBL27744010 | 0.81 | CYP3A4 (0.31) | NFE2L2CYP3A4CYP2C19CYP3A5GNRHR | |
| SCHEMBL28031578 | 0.80 | CYP3A4 (0.32) | NFE2L2CYP3A4CYP2C19CYP3A5GNRHR | |
| SCHEMBL27723314 | 0.80 | CYP3A4 (0.33) | CYP3A4CYP2C19CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130955-A | Preparation method of Vonoprazan fumarate | HAIKOU NANLU MEDICAL TECHNOLOGY CO LTD | 2015-12-09 | — | — | CN | claimed |
| CN-104926790-A | High-purity Vonoprazan Fumarate compound, intermediate and impurity thereof and preparation methods of high-purity Vonoprazan Fumarate compound, intermediate and impurity | JIANGSU AOSAIKANG PHARM CO LTD | 2015-09-23 | — | — | CN | claimed |
| CN-104860926-A | Preparation method of vonoprazan fumarate | ZHEJIANG CHENG YI PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | claimed |
| CN-105524046-A | Process for producing pyrrole compound | TAKEDA PHARMACEUTICAL | 2016-04-27 | — | — | CN | disclosed |
| CN-105130955-A | Preparation method of Vonoprazan fumarate | HAIKOU NANLU MEDICAL TECHNOLOGY CO LTD | 2015-12-09 | — | — | CN | disclosed |
| CN-105143187-A | Method for producing sulfonyl chloride compound | TAKEDA PHARMACEUTICAL | 2015-12-09 | — | — | CN | disclosed |
| CN-105085484-A | Preparation method of vonoprazan fumarate | NANJING GRITPHARMA CO LTD | 2015-11-25 | — | — | CN | disclosed |
| CN-104926790-A | High-purity Vonoprazan Fumarate compound, intermediate and impurity thereof and preparation methods of high-purity Vonoprazan Fumarate compound, intermediate and impurity | JIANGSU AOSAIKANG PHARM CO LTD | 2015-09-23 | — | — | CN | disclosed |
| CN-104860926-A | Preparation method of vonoprazan fumarate | ZHEJIANG CHENG YI PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |
| CN-104327051-A | Crystal form of fumarate of pyrrole derivative | SUNCADIA PHARMACEUTICALS CO LTD | 2015-02-04 | — | — | CN | disclosed |
| CN-102421753-B | Process for preparing azole compounds | TAKEDA PHARMACEUTICAL | 2014-12-31 | — | — | CN | disclosed |
| CN-104211618-A | Process for producing pyrrole compound | TAKEDA PHARMACEUTICAL | 2014-12-17 | — | — | CN | disclosed |
| CN-102421753-A | Process for preparing azole compounds | TAKEDA PHARMACEUTICAL | 2012-04-18 | — | — | CN | disclosed |
| CN-101300229-B | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors | TAKEDA PHARMACEUTICAL | 2011-10-05 | — | — | CN | disclosed |
| CN-101300229-A | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2008-11-05 | — | — | CN | disclosed |