Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933943 | 0.77 | ALDH1A1 (0.47) | IDO1KEAP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL27723772 | 0.77 | DTYMK (0.42) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL12405037 | 0.69 | MGAM (0.63) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL15133540 | 0.69 | IDO1 (0.75) | IDO1KEAP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL9220609 | 0.68 | MGAM (0.61) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL11228991 | 0.67 | IDO1 (0.50) | IDO1KEAP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL29475880 | 0.66 | IDO1 (1.00) | IDO1KEAP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL197490 | 0.66 | IDO1 (1.00) | IDO1KEAP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8006518 | 0.66 | IDO1 (1.00) | IDO1KEAP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL987442 | 0.66 | IDO1 (0.62) | IDO1KEAP1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273029-B | Bicyclic bisamide derivatives and their use as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2013-03-27 | — | — | CN | disclosed |
| CN-101273029-A | Bicyclic bisamide derivatives and their use as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-24 | — | — | CN | disclosed |