Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723971 | 0.91 | MAPT (0.33) | EPHX2TP53CNR2 | |
| SCHEMBL4592571 | 0.89 | CNR2 (0.38) | MEN1KMT2AATMHCRTR2POLB | |
| SCHEMBL27703389 | 0.85 | CNR1 (0.33) | MEN1KMT2AATMEPHX2POLB | |
| SCHEMBL27703381 | 0.83 | CNR1 (0.39) | EPHX2POLBROCK2LIMK1ROCK1 | |
| SCHEMBL4592616 | 0.82 | RAB9A (0.40) | MEN1KMT2APOLBCNR2 | |
| SCHEMBL4592431 | 0.81 | CNR2 (0.38) | POLBTP53CNR2 | |
| SCHEMBL28773080 | 0.80 | UTS2R (0.37) | TP53 | |
| SCHEMBL4592661 | 0.78 | PDK1 (0.33) | EPHX2 | |
| SCHEMBL4592810 | 0.78 | UTS2R (0.35) | CNR2 | |
| SCHEMBL4592518 | 0.77 | CYP3A4 (0.34) | EPHX2POLBTP53CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | claimed |
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | disclosed |