Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592616 | 0.91 | RAB9A (0.40) | CNR2EGFRERBB2RAB9APPARG | |
| SCHEMBL27723965 | 0.91 | MEN1 (0.33) | CNR2EPHX2TP53 | |
| SCHEMBL4592431 | 0.90 | CNR2 (0.38) | MAPTCNR1CNR2LMNATP53 | |
| SCHEMBL28773080 | 0.89 | UTS2R (0.37) | MAPTEGFRERBB2UTS2RTP53 | |
| SCHEMBL4592518 | 0.87 | CYP3A4 (0.34) | MAPTCNR1CNR2EGFRERBB2 | |
| SCHEMBL4592138 | 0.82 | CNR2 (0.34) | MAPTCNR1CNR2LMNATP53 | |
| SCHEMBL4592314 | 0.82 | ALOX5 (0.34) | MAPTCNR1CNR2EGFRERBB2 | |
| SCHEMBL4592556 | 0.82 | ALOX5 (0.34) | MAPTCNR1CNR2EGFRERBB2 | |
| SCHEMBL4592307 | 0.82 | ALOX5 (0.34) | MAPTCNR1CNR2EGFRERBB2 | |
| SCHEMBL4592810 | 0.82 | UTS2R (0.35) | CNR2UTS2RTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | claimed |
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | disclosed |