Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830009 | 0.71 | HCAR3 (0.44) | HCAR3CSNK2A1 | |
| SCHEMBL3580737 | 0.70 | HCAR3 (0.42) | HCAR3CSNK2A1 | |
| SCHEMBL3584391 | 0.67 | ALDH1A1 (0.37) | HCAR3 | |
| SCHEMBL2827434 | 0.66 | HCAR3 (0.46) | HCAR3 | |
| SCHEMBL2827656 | 0.65 | HCAR3 (0.45) | HCAR3 | |
| SCHEMBL8628930 | 0.62 | — | — | |
| SCHEMBL2443626 | 0.59 | LDHA (0.30) | — | |
| SCHEMBL9203287 | 0.59 | HCAR3 (0.35) | HCAR3 | |
| Lithium Ion SCHEMBL3580735 | 0.59 | HCAR3 (0.35) | HCAR3CSNK2A1 | |
| SCHEMBL8553614 | 0.59 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137653-B | Thiazole-4-carboxamide derivatives as MGLUR5 antagonists | HOFFMANN LA ROCHE | 2012-05-09 | — | — | CN | claimed |
| CN-101137653-A | Thiazole-4-carboxamide derivatives as MGLUR5 antagonists | HOFFMANN LA ROCHE (CH) | 2008-03-05 | — | — | CN | claimed |
| CN-101137653-B | Thiazole-4-carboxamide derivatives as MGLUR5 antagonists | HOFFMANN LA ROCHE | 2012-05-09 | — | — | CN | disclosed |
| CN-101379036-B | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | disclosed |
| CN-101379036-A | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE (CH) | 2009-03-04 | — | — | CN | disclosed |
| CN-101137653-A | Thiazole-4-carboxamide derivatives as MGLUR5 antagonists | HOFFMANN LA ROCHE (CH) | 2008-03-05 | — | — | CN | disclosed |