SCHEMBL27725622

SCHEMBL27725622

NC[Si]1(c2ccccc2)CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.33
DPP4 P27487 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
GRIN2D O15399 2/20 0.32
GRIN3B O60391 2/20 0.32
GRIA1 P42261 2/20 0.32
GRIA2 P42262 2/20 0.32
GRIA3 P42263 2/20 0.32
GRIA4 P48058 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
GRIN2B Q13224 2/20 0.32
GRIN2C Q14957 2/20 0.32
GRIN3A Q8TCU5 2/20 0.32
TAAR1 Q96RJ0 3/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
HTR2A P28223 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8026466 0.77 TP53 (0.30) MAOAMAOB
SCHEMBL9637584 0.73 TP53 (0.33) MAOAMAOB
SCHEMBL8042329 0.72 AOC3 (0.32)
SCHEMBL8455937 0.71 DNM1 (0.34) SMN1; SMN2
SCHEMBL5496477 0.70 MAPT (0.30) SMN1; SMN2
SCHEMBL20087445 0.70 MAPT (0.30) SMN1; SMN2
SCHEMBL3898942 0.70 MAPT (0.30) SMN1; SMN2
SCHEMBL27903706 0.69
SCHEMBL3798583 0.67 MAPT (0.32) SMN1; SMN2
SCHEMBL9230498 0.67 ALDH1A1 (0.35) SLC6A2SLC6A4SLC6A3TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101328189-B Preparation of bis(N,N-diethyl) aminomethyl phenyl silane UNIV HANGZHOU NORMAL 2010-12-08 CN disclosed
CN-101328189-A Preparation of bis(N,N-diethyl) aminomethyl phenyl silane UNIV HANGZHOU NORMAL (CN) 2008-12-24 CN disclosed