SCHEMBL3798583

SCHEMBL3798583

c1ccc([Si]2(c3ccccc3)CCCC2)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5496477 0.97 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL20087445 0.97 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL3898942 0.97 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8914562 0.94 MAPT (0.32) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL15637376 0.88 MAPT (0.35) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8977300 0.78
SCHEMBL18131846 0.78
SCHEMBL19273268 0.76 HTR2C (0.39) TSHR
SCHEMBL7715185 0.75 MAPT (0.35) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8015888 0.74 NPC1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10370588-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-08-06 US disclosed
US-20160190484-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20100022792-A1 SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES GROSS, PHILIP M. 2010-01-28 US disclosed
US-20080075973-A1 Red Electroluminescent Compounds And Organic Electroluminescent Device Using The Same GRACEL DISPLAY INC. (KR) 2008-03-27 US disclosed
WO-2005121274-A1 RED ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10370588-B2 Organometallic compound and organic light-emitting device including the same L1CAM, AP1M1, L3MBTL1 MAPT 890/4885HPGD 4024/4885SMN1; SMN2 1302/4885
US-20080075973-A1 Red Electroluminescent Compounds And Organic Electroluminescent Device Using The Same IK, NDUFS4, TYR MAPT 647/4885HPGD 2748/4885SMN1; SMN2 4348/4885
US-20160190484-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME L1CAM, AP1M1, L3MBTL1 MAPT 890/4885HPGD 4024/4885SMN1; SMN2 1302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.