Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958298 | 0.80 | NPC1 (0.33) | HTR7CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28769419 | 0.80 | AQP1 (0.37) | HTR7HTR1ACYP2A6NPC1RAB9A | |
| SCHEMBL14112625 | 0.68 | PRKAB2 (0.41) | HTR7HTR1ADPP4HTR2AHTR2C | |
| SCHEMBL8255768 | 0.68 | PRKAB2 (0.41) | HTR7HTR1ADPP4HTR2AHTR2C | |
| SCHEMBL4621228 | 0.68 | PRKAB2 (0.41) | HTR7HTR1ADPP4HTR2AHTR2C | |
| SCHEMBL5586510 | 0.68 | AQP1 (0.38) | HTR7HTR1ACYP2A6NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4619793 | 0.67 | PRKAB2 (0.40) | HTR7HTR1ADPP4HTR2AHTR2C | |
| SCHEMBL29802156 | 0.67 | CYP2A6 (0.67) | CYP2A6NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL671133 | 0.67 | CYP2A6 (0.67) | CYP2A6NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29883244 | 0.67 | CYP2A6 (0.67) | CYP2A6NPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203505-A | Chromane and chromene derivatives and uses thereof | WYETH CORP (US) | 2008-06-18 | — | — | CN | disclosed |