Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2122765 | 0.77 | — | — | |
| SCHEMBL16338744 | 0.76 | HTR6 (0.36) | — | |
| SCHEMBL1400976 | 0.71 | HTR2C (0.36) | HTR2CHTR2AMEN1ALDH1A1MAPT | |
| SCHEMBL27895099 | 0.67 | HTR2C (0.33) | HTR2CHTR2AMEN1ALDH1A1MAPT | |
| SCHEMBL2265420 | 0.67 | HTR2C (0.33) | HTR2CHTR2AMEN1ALDH1A1MAPT | |
| SCHEMBL6497810 | 0.67 | MEN1 (0.32) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL352142 | 0.65 | HTR2C (0.33) | HTR2CHTR2AMEN1ALDH1A1MAPT | |
| SCHEMBL3138747 | 0.65 | MEN1 (0.34) | HTR2CHTR2AMEN1ALDH1A1MAPT | |
| SCHEMBL5969664 | 0.64 | HTR2C (0.32) | HTR2CHTR2AMEN1ALDH1A1MAPT | |
| SCHEMBL3159987 | 0.64 | HTR6 (0.41) | HTR2CHTR2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208303-A | CGRP receptor antagonists | MERCK & CO INC (US) | 2008-06-25 | — | — | CN | disclosed |